Description

Boc-3-Amino-Thiophene-2-Carboxylic Acid is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical key building block for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing thiophene-based heterocycles.
• Peptidomimetics & Drug Discovery: Used to incorporate modified amino acid structures into peptides and small molecules to enhance stability, bioavailability, or biological activity.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and insecticides with thiophene motifs.
• Material Science Research: Employed in the creation of organic semiconductors, conductive polymers, and advanced functional materials.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules in proteomics and diagnostic assay development.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	Boc-3-Amino-Thiophene-2-Carboxylic Acid
CAS No.	101537-64-8
Molecular Formula	C10H13NO4S
Molecular Weight	243.28 g/mol
Synonyms	2-[(tert-Butoxycarbonyl)amino]-3-thiophenecarboxylic Acid; 3-[(tert-Butoxycarbonyl)amino]thiophene-2-carboxylic Acid; Boc-3-Amino-2-thiophenecarboxylic Acid; tert-Butyl (2-carboxythiophen-3-yl)carbamate; N-Boc-3-aminothiophene-2-carboxylic acid; 3-Amino-2-thiophenecarboxylic acid tert-butyl carbamate; 3-(Boc-amino)thiophene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our Boc-3-Amino-Thiophene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) documenting purity, appearance, and other critical parameters are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.