Description

3-Bromo-5-Phenyl-1,2,4-Thiadiazole is a specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a brominated thiadiazole ring with a phenyl substituent, making it a versatile precursor for constructing complex pharmacophores and functional materials. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for the development of new active ingredients and specialty chemicals. Its CAS number is 101495-43-6.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel drug candidates, particularly for molecules targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the creation of new herbicides, fungicides, and insecticides, where the thiadiazole moiety can contribute to biological activity.
• Material Science Research: Acts as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient heterocyclic core.
• Ligand and Catalyst Development: Employed in the synthesis of novel ligands for transition metal catalysis and in the preparation of organocatalysts.
• Chemical Biology Probes: Utilized to create molecular probes for studying biological pathways and enzyme functions, leveraging its potential for selective reactivity.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards for client-specific molecules.

Basic Information

Product Name	3-Bromo-5-Phenyl-1,2,4-Thiadiazole
CAS No.	101495-43-6
Molecular Formula	C8H5BrN2S
Molecular Weight	241.11 g/mol
Synonyms	3-Bromo-5-phenyl-1,2,4-thiadiazole; 5-Phenyl-3-bromo-1,2,4-thiadiazole; 1,2,4-Thiadiazole, 3-bromo-5-phenyl-; 101495-43-6; 3-Bromo-5-phenyl-[1,2,4]thiadiazole; NSC 405124; BRN 0579755
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Phenyl-1,2,4-Thiadiazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure compliance with stringent specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.