Description

5-Fluoro-1H-Indazole-6-Carboxylic Acid is a high-purity fluorinated indazole derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, agrochemical research, and material science.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for functionalized organic molecules used in organic light-emitting diodes (OLEDs) and other electronic materials.
• Medicinal Chemistry & SAR Studies: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Bioconjugation & Probe Development: The carboxylic acid group allows for conjugation to biomolecules, making it useful for developing fluorescent probes or diagnostic agents.

Basic Information

Product Name	5-Fluoro-1H-Indazole-6-Carboxylic Acid
CAS No.	101495-01-6
Molecular Formula	C8H5FN2O2
Molecular Weight	180.14 g/mol
Synonyms	5-Fluoro-1H-indazole-6-carboxylic acid; 6-Carboxy-5-fluoroindazole; 5-Fluoro-6-indazolecarboxylic acid; 1H-Indazole-6-carboxylic acid, 5-fluoro-; 5-Fluoroindazole-6-carboxylic acid; 101495-01-6; 5-Fluoro-1H-indazol-6-yl carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Fluoro-1H-Indazole-6-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with research and development grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.