Description

n-Benzyl-(3S)-Hydroxysuccinimide CAS NO 101469-91-4 is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic utility. Its value lies in its role as a versatile synthon for introducing the N-benzyl-protected (3S)-hydroxysuccinimide moiety into more complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries engaged in the development of active pharmaceutical ingredients (APIs), particularly those requiring stereochemical control.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the multi-step synthesis of complex drug molecules and bioactive compounds.
• Peptidomimetic Research: Used in the design and synthesis of peptide analogs and enzyme inhibitors where the succinimide scaffold is relevant.
• Asymmetric Synthesis: Serves as a starting material or intermediate in stereoselective chemical transformations to create enantiomerically pure products.
• Protecting Group Chemistry: The N-benzyl group can act as a protective group for amines in complex synthetic routes.
• Chemical Biology Probes: Utilized in the development of molecular probes and tools for studying biological processes.
• Custom Synthesis: A valuable building block for contract research and manufacturing organizations (CROs/CMOs) producing custom fine chemicals.

Basic Information

Product Name	n-Benzyl-(3S)-Hydroxysuccinimide
CAS No.	101469-91-4
Molecular Formula	C11H11NO3
Molecular Weight	205.21 g/mol
Synonyms	(3S)-1-Benzylpyrrolidine-2,5-dione; (S)-1-Benzyl-2,5-pyrrolidinedione; (S)-N-Benzyl-3-hydroxysuccinimide; (S)-1-Benzyl-3-hydroxypyrrolidine-2,5-dione; 1-Benzyl-(3S)-hydroxypyrrolidine-2,5-dione; N-Benzyl-L-malic imide; (S)-N-Benzylmalimide
EINECS	Contact for details

Quality Control

Our n-Benzyl-(3S)-Hydroxysuccinimide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity, correct stereochemistry, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.