Description

(S)-7-Methoxy-1-Methyl-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol is a chiral tetrahydroisoquinoline derivative, a high-value synthetic intermediate of significant importance in advanced pharmaceutical research and development. Its defined stereochemistry and functional groups make it a critical building block for constructing complex molecules with specific biological activity. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, particularly within the fields of central nervous system (CNS) and cardiovascular drug discovery.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs).
• Neurological Research: Used as a precursor in the synthesis of compounds targeting neurotransmitter pathways for potential CNS disorders.
• Cardiovascular Drug Development: Serves as a building block for molecules being investigated for cardiovascular applications.
• Asymmetric Synthesis: Employed in stereoselective synthesis due to its defined (S)-configuration, enabling the creation of enantiomerically pure final products.
• Medicinal Chemistry Research: Utilized in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery programs.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	(S)-7-Methoxy-1-Methyl-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol
CAS No.	101467-40-7
Molecular Formula	C11H15NO2
Molecular Weight	193.24 g/mol
Synonyms	(S)-6-Hydroxy-7-methoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline; (S)-7-Methoxy-1-methyl-1,2,3,4-tetrahydro-6-isoquinolinol; (S)-1-Methyl-6-hydroxy-7-methoxy-1,2,3,4-tetrahydroisoquinoline; (S)-6-OH-7-OMe-1-Me-THIQ; (S)-(-)-7-Methoxy-1-methyl-1,2,3,4-tetrahydroisoquinolin-6-ol; (S)-(-)-1-Methyl-6-hydroxy-7-methoxy-1,2,3,4-tetrahydroisoquinoline; (S)-enantiomer of 7-Methoxy-1-methyl-1,2,3,4-tetrahydroisoquinolin-6-ol
EINECS	Contact for details

Quality Control

Our (S)-7-Methoxy-1-Methyl-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with research-grade specifications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee traceability and support your critical R&D and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; appropriate handling procedures are required to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (S)-enantiomer
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.