Description

1-Bromo-2,2,3-Trimethylbutane is a specialized halogenated hydrocarbon building block valued for its unique sterically hindered structure and reactivity. This compound serves as a critical intermediate in advanced organic synthesis, particularly for introducing the bulky 2,2,3-trimethylbutyl moiety. It is primarily utilized by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially where steric hindrance is required to modulate biological activity or metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its branched alkyl chain can influence lipophilicity and environmental persistence.
• Organic Synthesis Reagent: Employed in alkylation reactions, nucleophilic substitutions, and as a precursor for organometallic reagents like Grignard or lithium derivatives.
• Material Science Research: Serves as a monomer or modifier in the development of specialty polymers with tailored properties such as increased thermal stability or altered solubility.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing complex terpene-derived aroma chemicals and musk analogs.
• Chemical Research & Development: A valuable tool for methodological studies in synthetic chemistry, including catalysis and reaction mechanism exploration.

Basic Information

Product Name	1-Bromo-2,2,3-Trimethylbutane
CAS No.	101419-71-0
Molecular Formula	C7H15Br
Molecular Weight	179.10 g/mol
Synonyms	2,2,3-Trimethyl-1-bromobutane; 1-Bromo-2,2,3-trimethylbutane; Neopentyl Bromide, Trimethyl-substituted; (2,2,3-Trimethylbutyl)bromide; Bromotrimethylbutane; tert-Butylisopropylmethyl Bromomethane
EINECS	Contact for details

Quality Control

Every batch of 1-Bromo-2,2,3-Trimethylbutane is manufactured and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including GC, HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from heat sources and incompatible materials. Due to its highly volatile nature, keep containers tightly sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.1%
Density (20°C)	~1.18 g/mL
Boiling Point	~150-155°C
Refractive Index (n20/D)	~1.455 - 1.460

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.