Description

4-(Bromomethyl)Benzo[D][1,3]Dioxole is a versatile and reactive brominated aromatic building block, essential for constructing complex molecular architectures in advanced organic synthesis. Its core value lies in the activated bromomethyl group, which facilitates efficient alkylation and functionalization reactions under mild conditions. This intermediate is particularly valuable for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) agents and other bioactive molecules containing the benzodioxole scaffold.
• Agrochemical Synthesis: Used in the development of new-generation pesticides, herbicides, and fungicides, where the benzodioxole moiety can enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Building block for synthesizing specialty polymers, dendrimers, and organic electronic materials with tailored properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and diagnostics.
• Flavor and Fragrance Industry: Intermediate for the production of complex aroma chemicals and synthetic musk compounds.

Basic Information

Product Name	4-(Bromomethyl)Benzo[D][1,3]Dioxole
CAS No.	101417-40-7
Molecular Formula	C9H7BrO2
Molecular Weight	227.06 g/mol
Synonyms	4-(Bromomethyl)-1,3-benzodioxole; 1,3-Benzodioxole, 4-(bromomethyl)-; 5-(Bromomethyl)-1,3-benzodioxole; Piperonyl Bromide; 3,4-(Methylenedioxy)benzyl Bromide; Bromomethylenedioxybenzene; NSC 403819
EINECS	Contact for details

Quality Control

Our 4-(Bromomethyl)Benzo[D][1,3]Dioxole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	65 - 68 °C
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.