Description

Brifentanil CAS NO 101345-71-5 is a potent synthetic opioid analgesic belonging to the fentanyl analogue class. This high-purity compound is critical for advanced pharmacological research and development, particularly in the study of opioid receptor mechanisms and analgesic pathways. It serves as an essential reference standard and intermediate for pharmaceutical R&D teams, analytical laboratories, and academic institutions focused on central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of opioid substances in method development, validation, and quality control testing.
• Biomedical Research: A key tool in preclinical studies investigating the pharmacology, toxicology, and metabolism of potent synthetic opioids.
• Analytical Chemistry: Serves as a certified reference material (CRM) for calibration in sophisticated analytical techniques like LC-MS/MS, GC-MS, and HPLC.
• Neuropharmacology Studies: Employed in receptor binding assays and functional studies to explore the structure-activity relationships (SAR) of fentanyl-related compounds.
• Forensic Science: Utilized as an analytical standard for the identification and confirmation of novel psychoactive substances (NPS) in forensic toxicology.
• Drug Discovery & Development: Acts as a chemical intermediate or a lead compound in the synthesis and development of new analgesic agents with targeted therapeutic profiles.

Basic Information

Product Name	Brifentanil
CAS No.	101345-71-5
Molecular Formula	C₂₀H₂₈N₂O₃
Molecular Weight	344.45 g/mol
Synonyms	Brifentanil; 4-Bromofentanyl; 4'-Bromo-fentanyl; 1-Phenethyl-4-(N-(4-bromophenyl)propionamido)piperidine; 4-Bromophenyl-1-phenethyl-4-(N-propionyl)piperidine; Brifentanyl; 4-Br-Fentanyl
EINECS	Contact for details

Quality Control

Every batch of Brifentanil is manufactured and analyzed under strict quality management systems to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with the high standards required for research and reference materials. A comprehensive Certificate of Analysis (COA) detailing purity, assay results, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture and contamination. Store under lock and key in accordance with all applicable local and international regulations for controlled substance handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%
Assay	97.0% - 102.0% (on anhydrous basis)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.