Description

[2R,3R,(-)]-1-Bromo-2,3-Pentanediol CAS NO 101221-91-4 is a high-purity, chiral bromohydrin derivative characterized by its specific stereochemistry at the 2 and 3 positions. This compound serves as a valuable chiral building block and intermediate in sophisticated organic synthesis, enabling the introduction of bromine and diol functionality with precise stereocontrol. It is primarily utilized by research institutions and pharmaceutical development companies engaged in the synthesis of active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals where stereochemical integrity is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, particularly in antiviral, antibacterial, and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides, where the specific stereoisomer can influence biological activity.
• Asymmetric Catalysis & Ligand Synthesis: Serves as a precursor for chiral ligands and catalysts used in enantioselective transformations.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & Industrial R&D: A critical reagent for methodological development in organic chemistry and process chemistry optimization.
• Polymer Chemistry: Potential monomer or cross-linking agent for creating polymers with specific stereoregular structures.

Basic Information

Product Name	[2R,3R,(-)]-1-Bromo-2,3-Pentanediol
CAS No.	101221-91-4
Molecular Formula	C5H11BrO2
Molecular Weight	183.05 g/mol
Synonyms	(2R,3R)-1-Bromo-2,3-pentanediol; (-)-1-Bromo-2,3-pentanediol; (2R,3R)-1-Bromopentane-2,3-diol; 1-Bromo-2,3-pentanediol, (2R,3R)-; (2R,3R)-1-Bromo-2,3-dihydroxypentane; Bromohydrin derivative of pentanediol; (2R,3R)-1-Bromopentanediol
EINECS	Contact for details

Quality Control

Our [2R,3R,(-)]-1-Bromo-2,3-Pentanediol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (e.e.) and chemical purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or otherwise opaque.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% e.e.
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.