Description

tert-Butyl-(2-Iodo-Ethoxy)-Dimethyl-Silane is a versatile organosilicon reagent featuring a protected hydroxyl group and a reactive iodoethyl linker. This compound matters as a critical building block in organic synthesis, enabling the controlled introduction of silicon-protected ethylene oxide units for the construction of complex molecules. Pharmaceutical researchers and fine chemical manufacturers need it for applications in medicinal chemistry, polymer science, and advanced material development.

Application

• Pharmaceutical Intermediates: Key synthon for the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates.
• Polymer & Material Science: Used as a functional monomer or cross-linking agent in the development of specialty silicones and advanced polymers.
• Organic Synthesis: Serves as a protected 2-hydroxyethyl anion equivalent in nucleophilic substitution and coupling reactions.
• Ligand & Catalyst Development: Employed in the preparation of novel silicon-containing ligands for catalytic systems.
• Surface Modification: Acts as a silylating agent for modifying surfaces with specific organic functionalities.
• Life Sciences Research: Utilized in bioconjugation and probe synthesis for biochemical and diagnostic applications.

Basic Information

Product Name	tert-Butyl-(2-Iodo-Ethoxy)-Dimethyl-Silane
CAS No.	101166-65-8
Molecular Formula	C8H19IOSi
Molecular Weight	286.23 g/mol
Synonyms	2-[(tert-Butyldimethylsilyl)oxy]ethyl Iodide; (2-Iodoethoxy)(tert-butyl)dimethylsilane; tert-Butyldimethyl(2-iodoethoxy)silane; 1-(tert-Butyldimethylsilyloxy)-2-iodoethane; TBDMS-2-iodoethyl ether; Silane, (2-iodoethoxy)(1,1-dimethylethyl)dimethyl-; (2-Iodoethoxy)-tert-butyldimethylsilane
EINECS	Contact for details

Quality Control

Our tert-Butyl-(2-Iodo-Ethoxy)-Dimethyl-Silane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and light-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.