Description

5-Bromo-3-Nitro-Thiophene-2-Carboxylic Acid is a high-purity, multifunctional heterocyclic building block of significant importance in advanced organic synthesis. Its unique structure, featuring bromo and nitro substituents on a thiophene carboxylic acid core, makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its reactive halogen and nitro groups for further functionalization.
• Material Science: Serves as a precursor for conductive polymers, organic semiconductors, and other electronic materials due to the thiophene backbone.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution, enabling the creation of diverse thiophene derivatives.
• Dye and Pigment Industry: Acts as an intermediate for synthesizing specialized dyes and pigments with specific optical properties.
• Academic & R&D: A valuable reagent for methodological studies and exploring new synthetic pathways in organic chemistry laboratories worldwide.

Basic Information

Product Name	5-Bromo-3-Nitro-Thiophene-2-Carboxylic Acid
CAS No.	101079-64-5
Molecular Formula	C5H2BrNO4S
Molecular Weight	251.04 g/mol
Synonyms	5-Bromo-3-nitro-2-thiophenecarboxylic acid; 2-Thiophenecarboxylic acid, 5-bromo-3-nitro-; 5-Bromo-3-nitrothiophene-2-carboxylic acid; 3-Nitro-5-bromothiophene-2-carboxylic acid; 5-Bromo-3-nitro-thiophene-2-carboxylic acid; BNTC; 101079-64-5 (CAS)
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Nitro-Thiophene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.