Description

Pyrrolo[2,3-b]indol-3a(1H)-ol,2,3,8,8a-tetrahydro-1-methyl-, (3aR,8aS)- is a complex, stereochemically defined heterocyclic compound that serves as a critical advanced intermediate in modern organic synthesis. Its value lies in its fused pyrroloindole scaffold, a privileged structure found in numerous biologically active molecules, making it indispensable for pharmaceutical research and development. This high-purity building block is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel compounds and exploring new therapeutic pathways.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new active ingredients for crop protection, leveraging its heterocyclic core.
• Fine Chemical Synthesis: Serves as a sophisticated precursor for creating specialty chemicals, dyes, and functional materials.
• Academic & Contract Research: Essential for methodological studies in organic chemistry, asymmetric synthesis, and heterocyclic chemistry research.
• Bioconjugate Chemistry: Potential use in creating labeled compounds or probes for biochemical and diagnostic applications.

Basic Information

Item	Detail
Product Name	Pyrrolo[2,3-b]indol-3a(1H)-ol,2,3,8,8a-tetrahydro-1-methyl-, (3aR,8aS)-
CAS No.	101053-34-3
Molecular Formula	C11H13NO
Molecular Weight	175.23 g/mol
Synonyms	(3aR,8aS)-1-Methyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-3a-ol; (3aR,8aS)-1-Methyl-2,3,8,8a-tetrahydro-3aH-pyrrolo[2,3-b]indol-3a-ol; Hexahydropyrrolo[2,3-b]indol-3a-ol derivative; Chiral pyrroloindolin-3a-ol; 1-Methylhexahydropyrrolo[2,3-b]indol-3a-ol; Advanced pharmaceutical intermediate (API) building block
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure high chemical and enantiomeric purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee reproducible performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for the specific grade.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.