Description

5-Chloro-Thiazole-2-Carboxylic Acid is a versatile heterocyclic building block with significant synthetic utility. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or metabolic disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole moiety.
• Material Science Research: Serves as a building block for creating functionalized polymers or organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	5-Chloro-Thiazole-2-Carboxylic Acid
CAS No.	101012-16-2
Molecular Formula	C4H2ClNO2S
Molecular Weight	163.58 g/mol
Synonyms	2-Thiazolecarboxylic acid, 5-chloro-; 5-Chloro-1,3-thiazole-2-carboxylic acid; 5-Chloro-2-carboxythiazole; 5-Chlorothiazole-2-carboxylic acid; 101012-16-2; 5-Chloro-2-thiazolecarboxylic acid; 5-Chloro-thiazole-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Chloro-Thiazole-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for high-value intermediate applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly closed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.