Description

n-(5-(p-Aminophenoxy)Pentyl)Maleimide is a specialized bifunctional organic compound featuring both a maleimide and an aromatic amine group. This unique structure makes it a valuable intermediate for the synthesis of advanced polymers and functional materials, particularly as a cross-linking agent or a site-specific conjugation handle. It is primarily sought after by researchers and manufacturers in the pharmaceutical, polymer science, and advanced materials sectors. The compound is supplied with a CAS number of 100958-17-6.

Application

• Pharmaceutical Conjugation: Key intermediate for synthesizing antibody-drug conjugates (ADCs) and other bioconjugates, linking payloads to proteins or peptides via the maleimide-thiol reaction.
• Polymer Modification & Cross-linking: Used to introduce reactive sites or cross-link polymer chains to enhance thermal stability, mechanical strength, or create hydrogels.
• Surface Functionalization: Employed to modify material surfaces (e.g., nanoparticles, biosensors) with amine-reactive groups for further chemical attachment.
• Dendrimer and Macromolecule Synthesis: Serves as a building block in the stepwise construction of complex, branched macromolecular architectures.
• Curing Agent for Epoxy Resins: Acts as a co-curing agent or modifier for epoxy systems, influencing the final network properties.
• Research & Development: A crucial reagent in organic synthesis and materials science R&D for creating novel functional molecules.

Basic Information

Product Name	n-(5-(p-Aminophenoxy)Pentyl)Maleimide
CAS No.	100958-17-6
Molecular Formula	C15H18N2O3
Molecular Weight	274.32 g/mol
Synonyms	N-[5-(4-Aminophenoxy)pentyl]maleimide; 1-[5-(4-Aminophenoxy)pentyl]-1H-pyrrole-2,5-dione; 4-(5-Maleimidopentyloxy)aniline; Maleimide, N-[5-(p-aminophenoxy)pentyl]-; p-Aminophenoxy Pentyl Maleimide; APPM; 5-(4-Aminophenoxy)pentyl Maleimide; N-(5-(4-Aminophenoxy)pentyl)maleimide
EINECS	Contact for details

Quality Control

Our n-(5-(p-Aminophenoxy)Pentyl)Maleimide is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.