Description

(1S,4S)-2,5-Diazabicyclo[2.2.1]Heptane Dihydrobromide is a high-purity, pharmaceutically relevant chiral building block and ligand. This compound is valued for its rigid, bicyclic diaza structure, which is crucial for imparting specific stereochemistry and binding properties in advanced chemical synthesis. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), catalysts, and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of complex drug candidates, particularly in medicinal chemistry programs.
• Catalyst Ligand: Used as a precursor or ligand in transition metal catalysis for enantioselective transformations.
• Chemical Research: Serves as a valuable scaffold in academic and industrial research for studying structure-activity relationships (SAR) and developing new methodologies.
• Agrochemical Synthesis: Potential application in the synthesis of chiral, biologically active compounds for crop protection.
• Material Science: Can be utilized in the development of specialized polymers or functional materials requiring specific molecular recognition sites.

Basic Information

Product Name	(1S,4S)-2,5-Diazabicyclo[2.2.1]Heptane Dihydrobromide
CAS No.	100944-14-7
Molecular Formula	C5H12N2 · 2HBr
Molecular Weight	263.98 g/mol
Synonyms	(1S,4S)-2,5-Diazabicyclo[2.2.1]heptane hydrobromide (1:2); (1S,4S)-2,5-Diazabicyclo[2.2.1]heptane dihydrobromide salt; (1S,4S)-2,5-Diazabicyclo[2.2.1]heptane, hydrobromide; endo-2,5-Diazabicyclo[2.2.1]heptane dihydrobromide; (1S,4S)-DABCO Dihydrobromide; (1S,4S)-2,5-Diazabicyclo[2.2.1]heptane HBr salt
EINECS	Contact for details

Quality Control

Our (1S,4S)-2,5-Diazabicyclo[2.2.1]Heptane Dihydrobromide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We support compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.