Description

2-Bromoacetylamino-3-(2-Chlorobenzoyl)-5-(2-Carbomethoxyethyl)Thiophene is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities. The CAS number for this product is 100827-79-0.

Application

This specialized intermediate serves as a key building block in sophisticated organic synthesis. Its primary applications include:

• Pharmaceutical Research & Development: As a crucial precursor in the synthesis of novel drug candidates, especially for central nervous system (CNS) and anti-inflammatory targets.
• Active Pharmaceutical Ingredient (API) Manufacturing: Used in the multi-step synthesis of complex APIs where its specific bromoacetyl and thiophene functionalities are essential.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization processes to develop new therapeutic agents.
• Contract Research Organizations (CROs): Supplied to CROs conducting custom synthesis and process development for client projects.
• Academic Research: Used in university and institutional labs for investigating new heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	2-Bromoacetylamino-3-(2-Chlorobenzoyl)-5-(2-Carbomethoxyethyl)Thiophene
CAS No.	100827-79-0
Molecular Formula	C₁₇H₁₅BrClNO₄S
Molecular Weight	444.73 g/mol
Synonyms	2-Bromo-N-[3-(2-chlorobenzoyl)-5-(2-methoxy-2-oxoethyl)thiophen-2-yl]acetamide; 5-(2-Carbomethoxyethyl)-2-bromoacetylamino-3-(2-chlorobenzoyl)thiophene; Thiophene derivative, 2-bromoacetylamino-3-(2-chlorobenzoyl)-5-(2-carbomethoxyethyl)-; 100827-79-0; 2-Bromoacetamido-3-(o-chlorobenzoyl)-5-(2-methoxycarbonylethyl)thiophene
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for this high-value intermediate. Production follows current Good Manufacturing Practice (cGMP) guidelines where applicable, and each batch is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing purity, identity, and impurity profiles to ensure consistency and reliability for your critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.