Description

2-Amino-3-(2-Chlorobenzoyl)-5-(2-Carbomethoxyethyl)Thiophene is a high-purity, synthetically valuable heterocyclic building block. This compound is a critical intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its unique thiophene and benzoyl motifs.
• Material Science: Serves as a building block for organic semiconductors, conductive polymers, or non-linear optical (NLO) materials due to its electron-rich thiophene core.
• Chemical Synthesis: Employed in academic and industrial research labs for methodological studies, such as cross-coupling reactions or heterocyclic functionalization.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on a commercial scale.

Basic Information

Product Name	2-Amino-3-(2-Chlorobenzoyl)-5-(2-Carbomethoxyethyl)Thiophene
CAS No.	100827-77-8
Molecular Formula	C15H14ClNO3S
Molecular Weight	323.79 g/mol
Synonyms	Methyl 3-[2-Amino-3-(2-chlorobenzoyl)thiophen-5-yl]propanoate; 5-(2-Methoxycarbonylethyl)-2-amino-3-(2-chlorobenzoyl)thiophene; 2-Amino-3-(2-chlorobenzoyl)-5-(2-methoxycarbonylethyl)thiophene; 2-Chloro-α-(2-amino-5-carbomethoxyethyl-3-thienyl)benzyl alcohol (keto form); Thiophene intermediate 100827-77-8
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-3-(2-Chlorobenzoyl)-5-(2-Carbomethoxyethyl)Thiophene is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, NMR, and MS analysis, to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.