Description

2H,4H-[1,3]Oxazino[4,3-A]Isoquinolin-4-One, 1,6,7,11B-Tetrahydro-1-(Hydroxymethyl)-9,10-Dimethoxy- is a complex heterocyclic organic compound of significant interest in advanced synthetic chemistry. This molecule serves as a key intermediate or building block for the research and development of novel pharmacologically active agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of new chemical entities, particularly those targeting neurological and cardiovascular pathways.

Application

• Pharmaceutical Intermediate: Critical building block in the multi-step synthesis of potential drug candidates, especially alkaloid-derived molecules.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new therapeutic agents with optimized efficacy and safety profiles.
• Organic Synthesis Reference Standard: Serves as a high-purity standard for analytical method development and validation in QC laboratories.
• Academic & Institutional Research: Utilized in universities and research institutes for studying complex heterocyclic reaction mechanisms and novel ring formations.
• Precursor for Bioactive Molecules: Foundation for synthesizing compounds with potential activity in central nervous system (CNS) disorders.
• Process Chemistry Development: Employed in scaling up and optimizing synthetic routes from milligram to kilogram scale for clinical trial material production.

Basic Information

Product Name	2H,4H-[1,3]Oxazino[4,3-A]Isoquinolin-4-One, 1,6,7,11B-Tetrahydro-1-(Hydroxymethyl)-9,10-Dimethoxy-
CAS No.	100783-51-5
Molecular Formula	C₁₆H₁₉NO₅
Molecular Weight	305.33 g/mol
Synonyms	1-(Hydroxymethyl)-9,10-dimethoxy-1,6,7,11b-tetrahydro-2H,4H-[1,3]oxazino[4,3-a]isoquinolin-4-one; 9,10-Dimethoxy-1-(hydroxymethyl)-1,6,7,11b-tetrahydro-4H-[1,3]oxazino[4,3-a]isoquinolin-4-one; Tetrahydroisoquinoline Oxazinone Derivative; (1R,11bR)-1-(Hydroxymethyl)-9,10-dimethoxy-1,6,7,11b-tetrahydro-2H,4H-[1,3]oxazino[4,3-a]isoquinolin-4-one (stereoisomer); Oxazino[4,3-a]isoquinolin-4-one derivative
EINECS	Contact for details

Quality Control

Our 2H,4H-[1,3]Oxazino[4,3-A]Isoquinolin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets the exacting standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.