Description

5-Amino-n-[(1-Ethylpyrrolidin-2-Yl)Methyl]-3-Methoxybenzo[B]Thiophene-2-Carboxamide Dihydrochloride is a high-purity, non-racemic pharmaceutical intermediate and research chemical of significant synthetic interest. This compound matters for its role as a key building block in the development of novel therapeutic agents, particularly within the central nervous system (CNS) and oncology research fields. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and advanced fine chemical manufacturers engaged in the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel drug candidates, particularly those targeting neurological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic entities.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in API manufacturing.
• Biochemical Tool Compound: Employed in preclinical research to investigate specific biological mechanisms and receptor interactions.
• Custom Synthesis: Starting material for the contract manufacturing of specialized, non-commercial compounds for research purposes.
• Process Development: Used in scaling up and optimizing synthetic routes for potential active pharmaceutical ingredients (APIs).

Basic Information

Product Name	5-Amino-n-[(1-Ethylpyrrolidin-2-Yl)Methyl]-3-Methoxybenzo[B]Thiophene-2-Carboxamide Dihydrochloride
CAS No.	100683-81-6
Molecular Formula	C₁₈H₂₆Cl₂N₄O₂S
Molecular Weight	433.39 g/mol
Synonyms	5-Amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-3-methoxybenzo[b]thiophene-2-carboxamide dihydrochloride; 5-Amino-3-methoxy-N-[(1-ethyl-2-pyrrolidinyl)methyl]benzo[b]thiophene-2-carboxamide dihydrochloride; 100683-81-6; Benzo[b]thiophene-2-carboxamide, 5-amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-3-methoxy-, dihydrochloride
EINECS	Contact for details

Quality Control

Our 5-Amino-n-[(1-Ethylpyrrolidin-2-Yl)Methyl]-3-Methoxybenzo[B]Thiophene-2-Carboxamide Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are available upon request for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.