Description

2,5-Bis(Diethoxyphosphoryl)Thiophene is a high-purity organophosphorus compound featuring a central thiophene ring symmetrically functionalized with diethoxyphosphoryl groups. This unique molecular architecture makes it a valuable specialty chemical intermediate for advanced material synthesis. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and organic electronics sectors for constructing complex molecules and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring phosphonate or thiophene motifs for bioactivity.
• Agrochemical Synthesis: Used in the development of advanced herbicides, insecticides, and fungicides where the phosphonate group enhances systemic activity and environmental stability.
• Ligand and Catalyst Precursor: Acts as a precursor for bidentate or multidentate ligands in coordination chemistry and catalysis, useful in cross-coupling and other transition metal-catalyzed reactions.
• Material Science Research: Employed in the synthesis of conjugated polymers and small molecules for organic semiconductors, OLEDs, and solar cells, where the thiophene-phosphonate combination can tune electronic properties.
• Flame Retardant Additive Development: Investigated as a potential monomer or additive for creating phosphorus-containing polymers with enhanced flame-retardant properties.
• Chemical Biology Probes: Utilized to create phosphonate-based analogs of biological molecules for enzyme inhibition studies and mechanistic investigations.

Basic Information

Product Name	2,5-Bis(Diethoxyphosphoryl)Thiophene
CAS No.	100651-98-7
Molecular Formula	C13H24O6P2S
Molecular Weight	370.33 g/mol
Synonyms	Diethyl 2,5-Thiophenediylbisphosphonate; 2,5-Thiophenediylbisphosphonic Acid Tetraethyl Ester; Tetraethyl (2,5-Thiophenediyl)bisphosphonate; Thiophene-2,5-diylbisphosphonic Acid Tetraethyl Ester; 2,5-Bis(diethylphosphono)thiophene; 2,5-Bis(phosphono)thiophene Tetraethyl Ester; 100651-98-7; 2,5-Thiophenediyldiphosphonic Acid Tetraethyl Ester
EINECS	Contact for details

Quality Control

Every batch of 2,5-Bis(Diethoxyphosphoryl)Thiophene is manufactured and tested under a strict quality management system. We ensure high purity and batch-to-batch consistency through advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider using an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.