Description

4-Hydroxy-2,2,6,6-Tetramethylpiperidine-D17-1-Oxyl is a deuterium-labeled, stable nitroxide radical derivative of the TEMPOL (4-hydroxy-TEMPO) family. This compound matters for its utility as a spin label and probe in advanced spectroscopic techniques, particularly Electron Paramagnetic Resonance (EPR) spectroscopy, where its isotopic labeling provides distinct analytical advantages. It is primarily needed by researchers and manufacturers in the pharmaceutical, biophysical chemistry, and material science sectors for studying molecular dynamics, oxidation processes, and polymer stabilization.

Application

• As a spin label and probe in Electron Paramagnetic Resonance (EPR) and Dynamic Nuclear Polarization (DNP) NMR spectroscopy for structural and dynamic studies of biomolecules.
• As a deuterated standard in quantitative mass spectrometry and analytical method development, ensuring high accuracy in detection and measurement.
• In polymer chemistry as a stabilizer and mediator for controlled radical polymerization processes (e.g., Nitroxide-Mediated Polymerization).
• For research on redox biology and free radical chemistry, investigating antioxidant mechanisms and oxidative stress.
• In the development of advanced materials, such as organic magnets and molecular switches.
• As a contrast agent in functional MRI research and other imaging applications.

Basic Information

Item	Details
Product Name	4-Hydroxy-2,2,6,6-Tetramethylpiperidine-D17-1-Oxyl
CAS No.	100326-46-3
Molecular Formula	C9D17NO2
Molecular Weight	190.33 g/mol (approx.)
Synonyms	4-Hydroxy-TEMPO-d17; 4-Hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl-d17; Perdeuterated 4-Hydroxy-TEMPO; 4-Hydroxy-2,2,6,6-tetramethyl-1-oxylpiperidine-d17; 4-Hydroxy-2,2,6,6-tetramethylpiperidin-1-oxyl-d17; 4-Hydroxy-TEMPOL-d17; 4-Hydroxy-2,2,6,6-tetramethylpiperidine-N-oxyl-d17; Deuterated TEMPOL radical
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-2,2,6,6-Tetramethylpiperidine-D17-1-Oxyl is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, EPR, and HPLC, to ensure high chemical purity and isotopic enrichment. Certificates of Analysis (COA) with detailed specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuteration Degree (NMR)	≥ 98 atom % D
EPR Signal	Characteristic triplet
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.