Description

4-Chloro-3-Nitrobenzenethiol is a versatile aromatic thiol building block characterized by its reactive thiol (-SH) group and electron-withdrawing nitro and chloro substituents. This compound is valued for its role as a key intermediate in the synthesis of more complex molecules, particularly in the development of pharmaceuticals and advanced materials. It is primarily sought by research chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing sulfur-containing heterocycles and functionalized aromatic systems.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), especially those containing benzothiazole or other sulfur heterocycles.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides where the thiol group enables specific modes of action.
• Material Science: Serves as a monomer or modifier in the development of polymers, liquid crystals, and organic electronic materials due to its aromatic structure and functional groups.
• Chemical Research: Employed in organic synthesis as a nucleophile for creating thioethers or as a precursor for metal-chelating ligands.
• Dye and Pigment Industry: Acts as an intermediate in the synthesis of sulfur-based dyes and organic pigments.

Basic Information

Product Name	4-Chloro-3-Nitrobenzenethiol
CAS No.	100191-28-4
Molecular Formula	C6H4ClNO2S
Molecular Weight	189.62 g/mol
Synonyms	3-Nitro-4-chlorobenzenethiol; 4-Chloro-3-nitrothiophenol; 1-Chloro-2-nitro-4-mercaptobenzene; Benzenethiol, 4-chloro-3-nitro-; 4-Chloro-3-nitrobenzenethiol; 4-Chloro-3-nitrothiophenol; 4-Chloro-3-nitrobenzene-1-thiol
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Nitrobenzenethiol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.