Description

3-(1-Phenyl-1H-Pyrazol-4-Yl)Propanoic Acid is a high-value organic intermediate featuring a pyrazole core linked to a phenyl group and a propanoic acid chain. This compound matters for its role as a versatile building block in the synthesis of more complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries seeking to create novel active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or as kinase inhibitors.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, or insecticides, leveraging the bioactivity of the pyrazole moiety.
• Ligand and Catalyst Development: Serves as a precursor for designing specialized ligands used in catalytic processes or metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, or polymers with specific electronic or optical properties.
• Chemical Biology Probes: Useful for constructing molecular probes to study biological pathways and protein functions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP guidelines.

Basic Information

Product Name	3-(1-Phenyl-1H-Pyrazol-4-Yl)Propanoic Acid
CAS No.	100142-73-2
Molecular Formula	C₁₂H₁₂N₂O₂
Molecular Weight	216.24 g/mol
Synonyms	3-(1-Phenyl-1H-pyrazol-4-yl)propanoic acid; 1-Phenyl-1H-pyrazole-4-propanoic acid; 3-(1-Phenyl-1H-pyrazol-4-yl)propionic acid; 4-(2-Carboxyethyl)-1-phenylpyrazole; 1-Phenyl-4-(2-carboxyethyl)pyrazole; β-(1-Phenyl-1H-pyrazol-4-yl)propionic Acid; NSC 405124; 100142-73-2
EINECS	Contact for details

Quality Control

Our 3-(1-Phenyl-1H-Pyrazol-4-Yl)Propanoic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.