Description

Ethyl 5-Bromo-3-Formyl-1H-Indole-2-Carboxylate is a high-value, multi-functional indole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its molecular architecture, featuring both bromo and formyl substituents, makes it an exceptionally versatile building block for constructing complex heterocyclic systems. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors, anti-cancer agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators that leverage the indole scaffold.
• Material Science Research: Serves as a building block for creating advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and fluorescent tags for studying biological processes.
• Academic & Contract Research: Essential for methodological development in organic synthesis, including cross-coupling reactions and heterocyclic chemistry research.
• Fine Chemical Production: Acts as a starting material for the manufacture of other specialized indole-based fine chemicals and custom synthesis projects.

Basic Information

Product Name	Ethyl 5-Bromo-3-Formyl-1H-Indole-2-Carboxylate
CAS No.	100123-25-9
Molecular Formula	C₁₂H₁₀BrNO₃
Molecular Weight	296.12 g/mol
Synonyms	5-Bromo-3-formyl-1H-indole-2-carboxylic acid ethyl ester; Ethyl 5-bromo-3-formylindole-2-carboxylate; 1H-Indole-2-carboxylic acid, 5-bromo-3-formyl-, ethyl ester; 5-Bromo-3-formylindole-2-carboxylic acid ethyl ester; 2-Carbethoxy-5-bromo-3-formylindole; 5-Bromo-3-carbaldehyde-1H-indole-2-carboxylate ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-Bromo-3-Formyl-1H-Indole-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. For custom synthesis or specific purity requirements (e.g., >98%, >99%), please contact our technical sales team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for prolonged procedures to ensure stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.