Description

2-Formyl-3-Thiophenecarboxylic Acid is a versatile heterocyclic building block featuring both aldehyde and carboxylic acid functional groups on a thiophene core. This bifunctional nature makes it a critical intermediate for synthesizing complex molecules in advanced research and industrial chemistry. It is primarily sought after by pharmaceutical, agrochemical, and material science R&D teams for constructing novel thiophene-based compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting central nervous system and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the thiophene moiety enhances biological activity.
• Organic Electronic Materials: Serves as a monomer or precursor for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Ligand and Catalyst Development: The functional groups allow for chelation to metal centers, useful in creating catalysts for cross-coupling and other organic transformations.
• Dye and Pigment Chemistry: Acts as a building block for synthesizing specialized dyes and pigments with unique optical properties.
• Academic and Contract Research: Essential reagent for methodological development and exploratory synthesis in university and CRO laboratories.

Basic Information

Product Name	2-Formyl-3-Thiophenecarboxylic Acid
CAS No.	19991-69-6
Molecular Formula	C6H4O3S
Molecular Weight	156.16 g/mol
Synonyms	3-Formylthiophene-2-carboxylic Acid; 3-Thiophenecarboxylic Acid, 2-formyl-; 2-Carboxy-3-thiophenecarboxaldehyde; 2-Formylthiophene-3-carboxylic Acid; Thiophene-2-carboxylic acid, 3-formyl-; 3-Formyl-2-thiophenecarboxylic Acid; 2-Formyl-3-thiophenecarboxylic acid; 3-Thiophenecarboxaldehyde, 2-carboxy-
EINECS	Contact for details

Quality Control

Our 2-Formyl-3-Thiophenecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.