Description

7-[3-[4-(4-Chlorophenylmethyl)-1-Piperazinyl]-2-Hydroxypropyl]-1,3-Dimethyl-7H-Purine-2,6(1H,3H)-Dione is a high-purity pharmaceutical intermediate and research chemical with a complex molecular structure designed for targeted biological activity. This compound matters for its role as a key synthetic precursor in the development of advanced therapeutic agents, particularly in neurological and cardiovascular research. It is primarily needed by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs) for preclinical and clinical development.
• Medicinal Chemistry Research: Used as a core scaffold or derivatization point for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Neurological Agent Development: Investigated for potential applications in targeting specific receptor pathways within the central nervous system.
• Cardiovascular Research: Serves as a research tool in studies aimed at modulating vascular and cardiac function.
• Biochemical Assay Standard: Employed as a reference standard in analytical method development and validation for pharmacokinetic studies.
• Contract Synthesis: Supplied to CMOs for custom synthesis projects under cGMP or non-GMP conditions, depending on project phase.

Basic Information

Product Name	7-[3-[4-(4-Chlorophenylmethyl)-1-Piperazinyl]-2-Hydroxypropyl]-1,3-Dimethyl-7H-Purine-2,6(1H,3H)-Dione
CAS No.	19971-93-8
Molecular Formula	C21H27ClN6O3
Molecular Weight	446.93 g/mol
Synonyms	1,3-Dimethyl-7-[3-[4-[(4-chlorophenyl)methyl]-1-piperazinyl]-2-hydroxypropyl]purine-2,6-dione; 7-[3-[4-(4-Chlorobenzyl)-1-piperazinyl]-2-hydroxypropyl]-1,3-dimethylxanthine; 1,3-Dimethyl-7-[3-[4-(4-chlorobenzyl)-1-piperazinyl]-2-hydroxypropyl]xanthine; 7-(3-(4-((4-Chlorophenyl)methyl)piperazin-1-yl)-2-hydroxypropyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione; CAS 19971-93-8; 1,3-Dimethyl-7-(3-(4-(4-chlorobenzyl)piperazin-1-yl)-2-hydroxypropyl)-3,7-dihydro-1H-purine-2,6-dione
EINECS	Contact for details

Quality Control

Our 7-[3-[4-(4-Chlorophenylmethyl)-1-Piperazinyl]-2-Hydroxypropyl]-1,3-Dimethyl-7H-Purine-2,6(1H,3H)-Dione is manufactured under strict quality management systems. Products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. We support development projects with custom purity grades and analytical method validation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions to prevent potential oxidation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.