Description

5-[(3,4-Dimethoxyphenyl)Methyl]-5,6,7,8-Tetrahydro-1,3-Dioxolo[4,5-G]Isoquinoline is a high-purity, complex heterocyclic compound that serves as a critical intermediate in advanced organic synthesis. Its unique molecular architecture, featuring fused isoquinoline and dioxole rings, makes it a valuable building block for pharmaceutical research and fine chemical manufacturing. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug discovery programs.
• Agrochemical Synthesis: Used in the synthesis of advanced crop protection agents and pesticides, leveraging its complex heterocyclic core for biological activity.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a building block for electron-transport or host materials in OLED displays and lighting due to its fused aromatic structure.
• Ligand and Catalyst Development: Utilized in organometallic chemistry to create novel ligands for asymmetric catalysis and transition metal complexes.
• Academic and Industrial Research: A valuable compound for methodological studies in organic chemistry, including novel cyclization and functionalization reactions.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals, dyes, and pigments requiring specific fused ring systems.

Basic Information

Product Name	5-[(3,4-Dimethoxyphenyl)Methyl]-5,6,7,8-Tetrahydro-1,3-Dioxolo[4,5-G]Isoquinoline
CAS No.	19918-74-2
Molecular Formula	C₂₁H₂₃NO₅
Molecular Weight	369.41 g/mol
Synonyms	1,3-Dioxolo[4,5-g]isoquinoline, 5-[(3,4-dimethoxyphenyl)methyl]-5,6,7,8-tetrahydro-; 5-[(3,4-Dimethoxybenzyl)-5,6,7,8-tetrahydro-1,3-dioxolo[4,5-g]isoquinoline; Tetrahydroaporphine derivative; NSC 339586; (6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl-1,3-benzodioxole; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 5-[(3,4-Dimethoxyphenyl)Methyl]-5,6,7,8-Tetrahydro-1,3-Dioxolo[4,5-G]Isoquinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements of research and process chemistry. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.