Description

(1S)-1,2,3,4-Tetrahydro-6,7-Dimethoxy-1-Methyl-2-(Phenylmethyl)Isoquinoline is a chiral tetrahydroisoquinoline derivative, a significant structural motif in medicinal chemistry. This compound matters as a versatile synthetic intermediate and a key building block for the development of novel pharmaceutical agents. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of alkaloids, central nervous system (CNS) active compounds, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex alkaloids and potential drug candidates targeting neurological pathways.
• Medicinal Chemistry Research: Serves as a chiral scaffold for structure-activity relationship (SAR) studies and the development of new therapeutic agents.
• Asymmetric Synthesis: Utilized as a building block in stereoselective synthesis due to its defined (1S) configuration.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Investigated for its interaction with biological targets such as enzymes and receptors in biochemical assays.
• Chemical Library Development: Incorporated into combinatorial and focused libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	(1S)-1,2,3,4-Tetrahydro-6,7-Dimethoxy-1-Methyl-2-(Phenylmethyl)Isoquinoline
CAS No.	19902-16-0
Molecular Formula	C20H25NO2
Molecular Weight	311.42 g/mol
Synonyms	(S)-1,2,3,4-Tetrahydro-6,7-dimethoxy-1-methyl-2-(phenylmethyl)isoquinoline; (S)-1,2,3,4-Tetrahydro-6,7-dimethoxy-1-methyl-2-benzylisoquinoline; (S)-1-Benzyl-6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline; (S)-Reticuline; (S)-Laudanosine derivative; (1S)-1-Methyl-2-benzyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-6,7-dimethoxy-1-methyl-2-(phenylmethyl)-(S)-isoquinoline
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) are available upon request, detailing specifications such as chiral purity (enantiomeric excess), chemical purity by HPLC, and residual solvent content. We adhere to cGMP principles for the manufacture of materials intended for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.