Description

4-Phenylbenzenethiol (CAS NO 19813-90-2) is a specialized aromatic thiol compound of significant interest in advanced organic synthesis and materials science. Its core value lies in its dual functionality, serving as a versatile building block for creating complex molecular architectures and as a critical ligand or precursor in catalytic systems. This high-purity intermediate is essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty polymer industries, where precise chemical functionality and reliable quality are paramount.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in sulfur-containing drug candidates.
• Ligand Synthesis: Used in the preparation of specialized ligands for transition metal catalysis, enabling more efficient and selective chemical transformations.
• Polymer Modification: Acts as a chain-transfer agent or functional monomer to introduce thiol groups into polymers, altering their physical properties and enabling further conjugation.
• Agrochemical Synthesis: Employed in the research and production of advanced herbicides, fungicides, and insecticides that require a biphenyl-thiol backbone.
• Material Science Research: Utilized in the creation of self-assembled monolayers (SAMs) on gold and other surfaces for sensor development and nanotechnology applications.
• Crosslinking Agent: Functions in formulations where controlled crosslinking via thiol-ene or thiol-epoxy reactions is required for coatings, adhesives, or resins.

Basic Information

Product Name	4-Phenylbenzenethiol
CAS No.	19813-90-2
Molecular Formula	C₁₂H₁₀S
Molecular Weight	186.27 g/mol
Synonyms	[1,1'-Biphenyl]-4-thiol; 4-Biphenylthiol; p-Phenylbenzenethiol; 4-Phenylthiophenol; p-Terphenyl-4'-thiol; 4-(Phenylthio)phenol; Biphenyl-4-thiol
EINECS	Contact for details

Quality Control

Our 4-Phenylbenzenethiol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant regulatory frameworks, including REACH, and can provide material for GMP-related applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, containers should be kept sealed and purged after each use to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	85 - 89 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.