Description

5,6,8,14-Tetradehydro-3-Hydroxy-2,6-Dimethoxy-17-Methylmorphinan-7-One is a high-purity synthetic intermediate belonging to the morphinan class of compounds. This product is critical for pharmaceutical research and development, particularly in the synthesis of specialized active pharmaceutical ingredients (APIs) and reference standards. It is primarily utilized by advanced research laboratories, pharmaceutical manufacturers, and fine chemical producers requiring precise and reliable building blocks for complex organic synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel opioid receptor ligands and other therapeutic agents within the morphinan series.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Biochemical Research: Employed in pharmacological studies to investigate receptor binding affinity, metabolic pathways, and structure-activity relationships (SAR).
• Process Chemistry: Serves as a critical building block in multi-step synthesis for developing new chemical entities (NCEs) and complex molecules.
• Academic Research: Utilized in university and institutional labs for advanced organic chemistry research and the development of new synthetic methodologies.

Basic Information

Product Name	5,6,8,14-Tetradehydro-3-Hydroxy-2,6-Dimethoxy-17-Methylmorphinan-7-One
CAS No.	19777-82-3
Molecular Formula	C₁₉H₂₃NO₄
Molecular Weight	329.39 g/mol
Synonyms	3-Hydroxy-2,6-dimethoxy-17-methyl-5,6,8,14-tetradehydromorphinan-7-one; 2,6-Dimethoxy-3-hydroxy-17-methyl-5,6,8,14-tetradehydromorphinan-7-one; 7-Oxo-5,6,8,14-tetradehydro-3-hydroxy-2,6-dimethoxy-17-methylmorphinan; Noroxymorphone dimethyl ketal (common name); 14-Hydroxynormorphinone dimethyl ketal
EINECS	Contact for details

Quality Control

Our 5,6,8,14-Tetradehydro-3-Hydroxy-2,6-Dimethoxy-17-Methylmorphinan-7-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets exacting standards for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.