Description

Chlorodifluoroacetic Acid, Lithium Salt is a specialized organofluorine compound that serves as a valuable reagent and building block in advanced chemical synthesis. Its importance lies in providing a source of the difluorocarboxylate moiety, enabling the introduction of fluorine atoms to modulate the properties of target molecules. This material is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients, as well as in materials science for creating specialty polymers and surfactants.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs to enhance metabolic stability, bioavailability, or membrane permeability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where fluorine incorporation can improve efficacy and environmental profile.
• Liquid Crystal & Polymer Chemistry: Serves as a monomer or modifier in the synthesis of fluorinated polymers and liquid crystal materials for electronics and high-performance coatings.
• Electrolyte Additive: Investigated for use as a component or additive in lithium-ion battery electrolytes to improve stability and performance.
• Organic Synthesis Reagent: Employed in nucleophilic substitution and coupling reactions to introduce the -CF2CO2- group into complex organic frameworks.
• Surface Active Agent Precursor: Acts as a starting material for synthesizing fluorinated surfactants and emulsifiers with unique surface properties.

Basic Information

Item	Detail
Product Name	Chlorodifluoroacetic Acid, Lithium Salt
CAS No.	19740-19-3
Molecular Formula	C2HClF2LiO2
Molecular Weight	128.42 g/mol
Synonyms	Lithium Chlorodifluoroacetate; Chlorodifluoroacetic Acid Lithium Salt; 2-Chloro-2,2-difluoroacetic Acid Lithium Salt; Lithium 2-Chloro-2,2-difluoroacetate; Monolithium Chlorodifluoroacetate; LiCDFA; CDFA-Li; Difluorochloracetic Acid Lithium Salt
EINECS	Contact for details

Quality Control

Our Chlorodifluoroacetic Acid, Lithium Salt is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with key parameters including assay, impurity profile, and moisture content. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Recommended storage temperature is 2-8°C for long-term stability. Keep away from incompatible materials such as strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.