Description

1-Iodoisoquinoline is a versatile halogenated heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its reactivity, serving as a key intermediate for constructing complex molecular architectures through cross-coupling reactions and functional group transformations. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries, enabling the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly those containing the isoquinoline scaffold for neurological and oncological targets.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, where the iodine atom facilitates further derivatization to create bioactive molecules.
• Material Science: Serves as a building block for organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) due to its planar structure and halogen functionality.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions such as Suzuki, Sonogashira, and Heck couplings to form carbon-carbon bonds.
• Ligand Synthesis: Utilized in the preparation of novel nitrogen-containing ligands for catalysis and coordination chemistry.
• Chemical Biology: Acts as a tagging or labeling reagent for probing biological systems and protein interactions.

Basic Information

Product Name	1-Iodoisoquinoline
CAS No.	19658-77-6
Molecular Formula	C9H6IN
Molecular Weight	255.06 g/mol
Synonyms	Isoquinoline, 1-iodo-; 1-Iodoisoquinoline; 1-Iodo-isoquinoline; Isoquinolin-1-yl iodide; 1-Iodoisoquinolin; 19658-77-6; 1-Jodisochinolin
EINECS	Contact for details

Quality Control

Our 1-Iodoisoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.