Description

(R)-(+)-1-Phenyl-1-Pentanol is a high-purity chiral secondary alcohol, characterized by its specific (R)-(+) enantiomeric configuration. This compound is a valuable chiral building block and resolving agent in asymmetric synthesis, where its defined stereochemistry is critical for inducing optical activity in target molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the development of active ingredients and advanced intermediates.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: Serves as a key starting material or intermediate for the production of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular active pharmaceutical ingredients (APIs).
• Asymmetric Catalyst and Ligand Precursor: Used in the preparation of chiral ligands for transition metal catalysts, enabling enantioselective hydrogenation, alkylation, and other critical transformations.
• Chiral Resolving Agent: Employed for the kinetic resolution of racemic mixtures of acids, amines, or other alcohols via esterification or other derivative formation.
• Agrochemical Intermediate: Functions as a building block for synthesizing chiral pesticides and herbicides with enhanced efficacy and environmental profile.
• Flavor and Fragrance Ingredient Synthesis: Used in the creation of stereochemically defined aroma chemicals where the specific enantiomer impacts the sensory profile.
• Academic and Industrial R&D: A fundamental reagent in methodological development for new asymmetric synthetic routes and stereochemistry studies.

Basic Information

Product Name	(R)-(+)-1-Phenyl-1-Pentanol
CAS No.	19641-53-3
Molecular Formula	C₁₁H₁₆O
Molecular Weight	164.24 g/mol
Synonyms	(R)-1-Phenyl-1-pentanol; (R)-(+)-1-Phenyl-1-pentanol; (R)-1-Phenylpentan-1-ol; (+)-(R)-1-Phenyl-1-pentanol; (R)-α-Ethylbenzenemethanol; (R)-1-Hydroxy-1-phenylpentane; (R)-Phenylpentyl alcohol; (R)-Benzenemethanol, α-ethyl-
EINECS	Contact for details

Quality Control

Our (R)-(+)-1-Phenyl-1-Pentanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high chemical and enantiomeric purity, meeting the stringent requirements for chiral intermediates. Standard testing includes chiral HPLC for enantiomeric excess (ee) determination, identity confirmation by IR and NMR, and impurity profiling. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Specific Rotation [α]²⁰D	+40.0° to +44.0° (c=1 in CHCl₃)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.