Description

Pyridine-D5 n-Oxide is a deuterated derivative of pyridine N-oxide, where all five hydrogen atoms are replaced by deuterium. This isotopic labeling is critical for applications requiring high chemical stability and minimal spectral interference, such as advanced NMR spectroscopy and reaction mechanism studies. It serves as an essential reagent and internal standard for researchers and quality control laboratories in the pharmaceutical, agrochemical, and analytical chemistry sectors.

Application

• NMR Spectroscopy: Used as a deuterated solvent or shift reference agent in nuclear magnetic resonance (NMR) studies due to its isotopic purity and distinct spectral properties.
• Mechanistic Studies: Acts as a probe or tracer in chemical and biochemical reaction mechanisms to elucidate pathways and kinetics.
• Pharmaceutical Research: Employed as an internal standard in quantitative analytical methods, including LC-MS and GC-MS, for drug development and metabolite identification.
• Material Science: Utilized in the synthesis of deuterated organic compounds and advanced materials where specific isotopic labeling is required.
• Catalysis Research: Serves as a ligand or additive in catalytic systems to study deuterium isotope effects.
• Quality Control & Reference Standards: Provides a high-purity reference material for calibrating analytical instruments and validating methods in compliance laboratories.

Basic Information

Product Name	Pyridine-D5 n-Oxide
CAS No.	19639-76-0
Molecular Formula	C5D5NO
Molecular Weight	99.12 g/mol
Synonyms	Perdeuteropyridine N-Oxide; Pyridine-d5 Oxide; (2H5)Pyridine 1-Oxide; Pyridine-N-oxide-d5; Deuteriopyridine N-Oxide; Pyridine-2,3,4,5,6-d5 1-Oxide; Pyridine-1-oxide-d5
EINECS	Contact for details

Quality Control

Our Pyridine-D5 n-Oxide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high isotopic purity. Each lot undergoes comprehensive analysis, including NMR, HPLC, and mass spectrometry, to confirm chemical identity, isotopic enrichment (typically >98 atom % D), and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.