Description

1H-Indole-4-Carboxaldehyde, 5-Hydroxy- is a versatile heterocyclic aldehyde building block of significant interest in advanced organic synthesis. Its unique indole core functionalized with both aldehyde and hydroxyl groups makes it a critical precursor for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in the areas of central nervous system (CNS) agents and anti-inflammatory compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its bioactive indole scaffold.
• Material Science Research: Serves as a precursor for functional organic materials, including ligands for metal-organic frameworks (MOFs) and organic semiconductors.
• Biochemical Probe Development: Utilized in medicinal chemistry to create fluorescent probes or enzyme inhibitors for biological pathway studies.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry and for custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Product Name	1H-Indole-4-Carboxaldehyde, 5-Hydroxy-
CAS No.	19502-27-3
Molecular Formula	C9H7NO2
Molecular Weight	161.16 g/mol
Synonyms	5-Hydroxy-1H-indole-4-carboxaldehyde; 5-Hydroxyindole-4-carboxaldehyde; 4-Formyl-5-hydroxyindole; 5-Hydroxy-4-indolecarboxaldehyde; 5-Hydroxy-1H-indole-4-carbaldehyde; 19502-27-3; 5-Hydroxyindole-4-carbaldehyde
EINECS	Contact for details

Quality Control

Our 1H-Indole-4-Carboxaldehyde, 5-Hydroxy- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) are available for every batch upon request, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This product is easily oxidized and light-sensitive.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.