Description

8-Hydroxy-7-Methoxycoumarin is a functionalized coumarin derivative, a versatile organic compound known for its distinctive fused benzopyrone ring structure. This compound serves as a critical building block and pharmacophore in advanced organic synthesis and pharmaceutical research. It is primarily utilized by research institutions, pharmaceutical developers, and fine chemical manufacturers for applications in drug discovery, material science, and as a reference standard.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting inflammation, cancer, and neurological disorders.
• Fluorescent Probe & Dye Synthesis: Used in the development of fluorescent markers, sensors, and optical brightening agents due to its inherent luminescent properties.
• UV Absorber & Photostabilizer: Incorporated into formulations for coatings, polymers, and cosmetics to enhance resistance to ultraviolet light degradation.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and as a tool compound for investigating biological pathways.
• Organic Synthesis Building Block: Utilized for constructing more complex heterocyclic compounds and natural product analogs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical and chemical analysis.

Basic Information

Product Name	8-Hydroxy-7-Methoxycoumarin
CAS No.	19492-03-6
Molecular Formula	C10H8O4
Molecular Weight	192.17 g/mol
Synonyms	7-Methoxy-8-hydroxycoumarin; 8-Hydroxy-7-methoxy-2H-chromen-2-one; 7-Methoxyumbelliferone; 7-Methoxy-8-hydroxy-2H-1-benzopyran-2-one; Fraxetin (common name); 8-Hydroxy-7-methoxy-2H-1-benzopyran-2-one; 7-Methoxy-8-hydroxycoumarin
EINECS	243-112-9

Quality Control

Our 8-Hydroxy-7-Methoxycoumarin is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and loss on drying. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	228°C - 232°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.