Description

2-Iodo-2-Methylpropionitrile is a versatile halogenated nitrile building block, primarily recognized for its utility as an alkylating agent and radical initiator in organic synthesis. Its value lies in its ability to introduce the tert-butyl nitrile moiety, a key functional group for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where it facilitates the development of novel active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring tert-butyl or cyano-substituted structures.
• Polymer Chemistry: Serves as a functional monomer or initiator in the production of specialty polymers and resins with tailored properties.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and other crop protection agents.
• Organic Synthesis Reagent: Acts as a radical source or alkylating agent in various carbon-carbon bond formation reactions and cyclization processes.
• Material Science Research: Employed in the development of novel organic electronic materials and liquid crystals.
• Cross-coupling Reactions: A potential substrate in palladium-catalyzed reactions for creating complex organic molecules.

Basic Information

Product Name	2-Iodo-2-Methylpropionitrile
CAS No.	19481-79-9
Molecular Formula	C5H8IN
Molecular Weight	209.03 g/mol
Synonyms	2-Iodo-2-methylpropiononitrile; (2-Iodo-2-methylpropyl) cyanide; α-Iodoisobutyronitrile; 2-Iodoisobutyronitrile; 2-Cyano-2-iodopropane; Iodopivalonitrile; tert-Butyl iodide cyanide; 2-Methyl-2-iodopropionitrile
EINECS	243-107-6

Quality Control

Our 2-Iodo-2-Methylpropionitrile is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions. Keep separated from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Gravity	1.6 - 1.8 g/mL @ 20°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.