Description

L-Alanine-N,N,o-D3 is a stable isotope-labeled derivative of the essential amino acid L-alanine, specifically deuterated at the amino and α-carbon positions. This high-purity compound is critical for applications requiring precise metabolic tracing and structural elucidation without isotopic interference. It is primarily utilized by research institutions and pharmaceutical companies engaged in advanced NMR spectroscopy, mass spectrometry, and metabolic pathway studies.

Application

• Internal standard for quantitative analysis in LC-MS and GC-MS applications.
• Tracer molecule in deuterium metabolic imaging (DMI) and magnetic resonance spectroscopy (MRS) for biomedical research.
• Precursor for synthesizing deuterated peptides and proteins for structural biology studies.
• Use in metabolic flux analysis to investigate amino acid metabolism in cell cultures and model organisms.
• Labeled standard in pharmaceutical development for drug metabolism and pharmacokinetics (DMPK) studies.
• Research tool in isotope-edited NMR experiments to simplify complex spectra and study molecular interactions.

Basic Information

Product Name	L-Alanine-N,N,o-D3
CAS No.	19470-97-4
Molecular Formula	C₃H₄D₃NO₂
Molecular Weight	92.11 g/mol
Synonyms	(2S)-2-Azanyl-3,3,3-trideuteriopropanoic acid; L-Alanine-2,3,3,3-d4 (common naming); L-2-Aminopropionic acid-N,N,o-D3; (S)-Alanine-N,N,o-D3; Alanine-d3; Deuterated L-alanine; L-Alanine-d3; [2H3]-L-Alanine
EINECS	Contact for details

Quality Control

Our L-Alanine-N,N,o-D3 is manufactured under strict quality systems to ensure exceptional isotopic and chemical purity, suitable for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (atom % D), chemical purity, and spectroscopic confirmation. We adhere to rigorous in-house specifications designed to meet the demands of advanced research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant or inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Optical Rotation	+13.5° to +15.5° (c=1 in H₂O)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.