Description

Cyclopropyl Iodide is a versatile and highly reactive alkyl halide building block essential for organic synthesis. Its strained three-membered cyclopropyl ring enables unique reactivity, making it a critical intermediate for constructing complex molecular architectures. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce the cyclopropyl moiety, a privileged structure known for enhancing metabolic stability and biological activity in active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) containing the cyclopropyl group, used in antiviral, antibacterial, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Employed in the production of advanced herbicides, fungicides, and insecticides where the cyclopropyl ring improves efficacy and environmental profile.
• Cross-Coupling Reactions: Serves as a pivotal substrate in palladium-catalyzed cross-coupling reactions (e.g., Negishi, Suzuki-Miyaura) for carbon-carbon bond formation.
• Material Science Research: Used in the development of novel organic semiconductors, liquid crystals, and polymers with tailored electronic properties.
• Organic Synthesis Reagent: A fundamental reagent for ring-opening, nucleophilic substitution, and cycloaddition reactions in academic and industrial R&D laboratories.
• Derivatization Agent: Utilized for the functionalization of complex molecules in medicinal chemistry for structure-activity relationship (SAR) studies.

Basic Information

Product Name	Cyclopropyl Iodide
CAS No.	19451-11-7
Molecular Formula	C3H5I
Molecular Weight	167.98 g/mol
Synonyms	Cyclopropyliodide; Iodocyclopropane; Cyclopropyl iodide; (Iodomethyl)ethylene; Cyclopropane, iodo-; Monoidocyclopropane
EINECS	243-097-8

Quality Control

Our Cyclopropyl Iodide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We adhere to cGMP standards where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at 2-8°C (refrigerated) or as specified on the label. Due to its light-sensitive and highly volatile nature, containers should be kept tightly sealed and allowed to reach ambient temperature before opening to minimize moisture ingress and pressure change.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Gravity	1.80 - 1.85
Refractive Index	1.550 - 1.556

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.