Description

trans-1-Phenyl-4-tert-Butylcyclohexanol is a high-purity, sterically hindered alcohol derivative of significant industrial interest. This compound serves as a versatile chiral intermediate and building block in advanced organic synthesis. It is particularly valuable for the pharmaceutical, agrochemical, and specialty chemical industries, where its defined stereochemistry and robust structure are leveraged to create complex, high-performance molecules.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), especially in steroidal and other complex therapeutic agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators where specific stereochemistry impacts biological activity.
• Liquid Crystal Materials: Serves as a precursor or dopant in the manufacture of liquid crystal displays (LCDs) due to its rigid, substituted cyclohexane core.
• Fragrance & Flavor Chemistry: Acts as an intermediate for synthesizing musky or woody aroma chemicals, leveraging the stability of the tert-butyl and phenyl groups.
• Polymer Additives: Potential use as a light stabilizer or antioxidant precursor in polymer formulations, where the hindered phenol structure can inhibit degradation.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for studying stereoselective reactions and developing new catalytic methodologies.

Basic Information

Product Name	trans-1-Phenyl-4-tert-Butylcyclohexanol
CAS No.	19437-01-5
Molecular Formula	C₁₆H₂₄O
Molecular Weight	232.36 g/mol
Synonyms	4-tert-Butyl-1-phenylcyclohexanol (trans-); trans-4-(tert-Butyl)-1-phenylcyclohexanol; 1-Phenyl-4-tert-butylcyclohexanol (trans-); (1r,4r)-4-tert-Butyl-1-phenylcyclohexan-1-ol; (trans)-1-Phenyl-4-(1,1-dimethylethyl)cyclohexanol; NSC 163022; 1-Phenyl-4-(tert-butyl)cyclohexanol, trans-
EINECS	Contact for details

Quality Control

Our trans-1-Phenyl-4-tert-Butylcyclohexanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, GC, and NMR to ensure high chemical and isomeric purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee consistent quality and traceability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isomeric Purity (trans-)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.