Description

2-Amino-5-Methyl-Thiophene-3-Carboxylic Acid Methyl Ester is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of complex pharmacologically active molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel thiophene-based scaffolds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the thiophene moiety for bioactivity.
• Material Science Research: Serves as a monomer or building block for creating conjugated polymers and organic electronic materials due to its electron-rich thiophene core.
• Dye and Pigment Manufacturing: Employed in the synthesis of specialized dyes and organic pigments where the amino and ester functionalities allow for further chemical modifications.
• Chemical Research & Development: A versatile starting material for medicinal chemistry and process chemistry for exploring new chemical entities and optimizing synthetic routes.

Basic Information

Product Name	2-Amino-5-Methyl-Thiophene-3-Carboxylic Acid Methyl Ester
CAS No.	19369-53-0
Molecular Formula	C7H9NO2S
Molecular Weight	171.22 g/mol
Synonyms	Methyl 2-amino-5-methylthiophene-3-carboxylate; 2-Amino-5-methyl-3-thiophenecarboxylic acid methyl ester; 5-Methyl-2-aminothiophene-3-carboxylic acid methyl ester; 3-Thiophenecarboxylic acid, 2-amino-5-methyl-, methyl ester; Methyl 5-methyl-2-aminothiophene-3-carboxylate; 2-Amino-5-methylthiophene-3-methyl carboxylate; AMTCME
EINECS	Contact for details

Quality Control

Our production of 2-Amino-5-Methyl-Thiophene-3-Carboxylic Acid Methyl Ester adheres to stringent in-process controls and final batch testing to ensure consistent high quality and purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the rigorous demands of GMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.