Description

3-Bromotetrahydrofuran is a versatile halogenated cyclic ether, widely recognized as a key building block in organic synthesis. Its primary value lies in its ability to act as a reactive alkylating agent and a precursor for more complex heterocyclic compounds, enabling the creation of high-value pharmaceuticals and advanced materials. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to introduce the tetrahydrofuran moiety or a bromine handle for further functionalization.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs containing tetrahydrofuran rings.
• Agrochemical Synthesis: Used in the manufacturing of herbicides, fungicides, and other crop protection agents.
• Polymer & Material Science: Serves as a monomer or modifying agent for producing specialty polymers and functional materials.
• Organic Synthesis Reagent: Employed as an alkylating agent in nucleophilic substitution reactions and in the preparation of Grignard reagents.
• Ligand & Catalyst Development: Useful for synthesizing novel ligands and organometallic catalysts used in asymmetric synthesis.
• Chemical Research: A valuable tool in academic and industrial research laboratories for exploring new synthetic methodologies.

Basic Information

Product Name	3-Bromotetrahydrofuran
CAS No.	19311-37-6
Molecular Formula	C4H7BrO
Molecular Weight	151.00 g/mol
Synonyms	3-Bromooxolane; Tetrahydro-3-bromofuran; 3-Bromo-tetrahydrofuran; 3-Bromofuranidine; 3-Bromo-oxacyclopentane; α-Bromotetrahydrofuran; 3-Br-THF
EINECS	242-943-8

Quality Control

Our 3-Bromotetrahydrofuran is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive quality documentation, including a detailed Certificate of Analysis (COA) for each lot, which confirms identity, purity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is 2-8°C to maximize shelf life and stability. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.480 - 1.490
Density (20°C)	1.60 - 1.65 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.