Description

1-Bromo-2,3,4,6-Tetra-Acetyl-β-D-Galactoside is a key glycosyl donor intermediate, specifically a peracetylated galactosyl bromide, widely used in stereoselective glycosylation reactions. Its value lies in its role as a versatile building block for the synthesis of complex oligosaccharides, glycoconjugates, and glycomimetics, enabling precise control over anomeric configuration. This compound is essential for researchers and manufacturers in pharmaceutical development, carbohydrate chemistry, and the production of diagnostic reagents and bioactive molecules.

Application

• Glycosylation Reagent: A crucial donor for the Koenigs-Knorr and related glycosylation methods to construct β-linked galactosidic bonds.
• Pharmaceutical Intermediates: Synthesis of active pharmaceutical ingredients (APIs) and prodrugs that contain galactose moieties.
• Oligosaccharide & Glycoconjugate Synthesis: Building block for creating complex carbohydrates, glycoproteins, and glycolipids for biological studies.
• Diagnostic Reagent Production: Used in manufacturing substrates and probes for enzymatic assays and diagnostic kits targeting galactosidases.
• Glycomimetics & Drug Discovery: Key starting material for developing carbohydrate-based drugs, inhibitors, and vaccine candidates.
• Biochemical Research: Tool compound for studying enzyme mechanisms, cell-surface interactions, and carbohydrate-mediated biological processes.

Basic Information

Item	Details
Product Name	1-Bromo-2,3,4,6-Tetra-Acetyl-β-D-Galactoside
CAS No.	19285-38-2
Molecular Formula	C₁₆H₂₃BrO₁₀
Molecular Weight	455.25 g/mol
Synonyms	2,3,4,6-Tetra-O-acetyl-α-D-galactopyranosyl bromide; Acetobromo-α-D-galactose; α-D-Galactopyranosyl bromide, 2,3,4,6-tetraacetate; Galactose pentaacetate bromide; Bromo-2,3,4,6-tetra-O-acetyl-α-D-galactopyranose; 1-Bromo-2,3,4,6-tetra-O-acetyl-α-D-galactopyranose; AcOBrGal; α-Acetobromogalactose
EINECS	Contact for details

Quality Control

Our 1-Bromo-2,3,4,6-Tetra-Acetyl-β-D-Galactoside is produced and tested under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity suitable for synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems support compliance with relevant standards for research and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under anhydrous conditions when possible. Keep the container tightly sealed in a desiccator for long-term storage to maintain stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	88 - 92 °C
Specific Rotation [α]²⁰D	+190° to +200° (c=1 in CHCl₃)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.