Description

Acetyl Chloride-D3 is a deuterated derivative of acetyl chloride, where three hydrogen atoms are replaced by deuterium, serving as a critical stable isotope-labeled reagent. This compound is essential for applications requiring precise molecular tracking and analysis, offering superior signal differentiation in spectroscopic studies. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors for synthesis, metabolic studies, and as an internal standard.

Application

• Pharmaceutical Research & Development: Used as a deuterated building block in the synthesis of isotopically labeled drug candidates for pharmacokinetic and metabolic studies.
• Analytical Chemistry: Serves as a crucial internal standard in quantitative NMR (qNMR), LC-MS, and GC-MS analysis to ensure accuracy and compensate for instrument variability.
• Agrochemical Synthesis: Employed in the development of deuterated pesticides and herbicides to study environmental fate, degradation pathways, and metabolic products.
• Material Science Research: Acts as a precursor or derivatization agent in the synthesis of novel deuterated polymers or organic electronic materials for structural analysis.
• Metabolomics & Proteomics: Facilitates the tracking and identification of biochemical pathways in complex biological systems through isotope labeling techniques.

Basic Information

Product Name	Acetyl Chloride-D3
CAS No.	19259-90-6
Molecular Formula	C2D3ClO
Molecular Weight	81.51 g/mol
Synonyms	Deuteroacetyl Chloride; Acetyl-d3 Chloride; [2H3]Acetyl Chloride; Acetic-d3 Acid Chloride; (2H3)Acetyl Chloride; CD3COCl; Acetyl Chloride (D3); Trichloromethanone-d3
EINECS	Contact for details

Quality Control

Our Acetyl Chloride-D3 is produced under stringent conditions to ensure high isotopic purity and chemical integrity. Each batch undergoes comprehensive analysis, including NMR for deuterium enrichment and purity, GC for chemical purity, and residual solvent testing. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with specifications for research and industrial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its highly volatile and hygroscopic nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Deuterium Enrichment (NMR)	≥ 99.0 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.