Description

1H-Indole-3-Carbonyl Cyanide is a versatile heterocyclic building block of significant interest in synthetic organic chemistry. This compound serves as a key intermediate for constructing complex molecular architectures, particularly in the development of pharmaceuticals and agrochemicals. It is primarily utilized by research institutions and industrial R&D departments focused on medicinal chemistry and fine chemical synthesis. The material is supplied to meet the stringent purity requirements of advanced chemical manufacturing.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of indole-based drug candidates, including potential kinase inhibitors and receptor modulators.
• Agrochemical Research: Used in developing novel active ingredients for crop protection products, leveraging its heterocyclic core.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to introduce the indole-carbonyl cyanide functional group into target molecules.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials.
• Bioconjugation Chemistry: Potential use in creating labeled probes or linkers for biochemical applications due to its reactive cyanide and carbonyl groups.

Basic Information

Product Name	1H-Indole-3-Carbonyl Cyanide
CAS No.	19194-62-8
Molecular Formula	C10H6N2O
Molecular Weight	170.17 g/mol
Synonyms	Indole-3-carbonyl cyanide; 3-Cyanoformylindole; 3-Cyanocarbonylindole; 1H-Indole-3-carboxylic acid cyanide; 3-Indolecarbonyl cyanide; 3-Cyanocarbonyl-1H-indole; 1H-Indole-3-glyoxylonitrile; 3-(Cyanocarbonyl)indole
EINECS	Contact for details

Quality Control

Our 1H-Indole-3-Carbonyl Cyanide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods, to ensure it meets exacting standards for research and development use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.