Description

2-(Bromomethyl)-2-(Hydroxymethyl)-1,3-Propanediol CAS NO 19184-65-7 is a versatile brominated polyol intermediate with a unique trifunctional structure. This compound is valued for its ability to introduce both bromine and hydroxyl functional groups into target molecules, enabling precise chemical modifications. It is primarily sought after by researchers and manufacturers in the pharmaceutical, polymer, and specialty chemical industries for applications ranging from flame retardant synthesis to the development of novel cross-linking agents and pharmaceutical building blocks.

Application

• Pharmaceutical Intermediate: Serves as a key building block for synthesizing active pharmaceutical ingredients (APIs) and prodrugs, particularly where bromine acts as a leaving group for further functionalization.
• Polymer Chemistry: Used as a cross-linking agent or monomer in the production of specialty polymers, resins, and coatings, imparting specific properties like flame retardancy or modified solubility.
• Flame Retardant Synthesis: Acts as a precursor in the manufacture of brominated flame retardants for plastics, textiles, and electronic materials.
• Organic Synthesis: Employed in nucleophilic substitution reactions and as a scaffold for constructing complex polyfunctional molecules in research and development.
• Surface Modifier: Can be used to functionalize surfaces or nanoparticles by providing reactive bromomethyl and hydroxymethyl groups for subsequent conjugation.
• Ligand and Chelator Preparation: Useful in synthesizing novel ligands, chelating agents, or dendrimers due to its multiple reactive sites.

Basic Information

Product Name	2-(Bromomethyl)-2-(Hydroxymethyl)-1,3-Propanediol
CAS No.	19184-65-7
Molecular Formula	C5H11BrO3
Molecular Weight	199.04 g/mol
Synonyms	2-(Bromomethyl)-2-(hydroxymethyl)propane-1,3-diol; 2-Bromomethyl-2-hydroxymethyl-1,3-propanediol; Tris(hydroxymethyl)aminomethane bromomethyl derivative; Brominated Tris base derivative; 1,3-Propanediol, 2-(bromomethyl)-2-(hydroxymethyl)-; Bromoneopentyl glycol (common name); 2,2-Bis(bromomethyl)propane-1,3-diol related compound
EINECS	242-857-3

Quality Control

Our 2-(Bromomethyl)-2-(Hydroxymethyl)-1,3-Propanediol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets precise customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.