Description

Tiglic Acid-D3 is a stable isotope-labeled analog of tiglic acid, where three hydrogen atoms are replaced by deuterium. This high-purity compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring precise and accurate analytical measurements. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, agrochemical, and analytical chemistry sectors for method development and validation.

Application

• Used as a deuterated internal standard for the accurate quantification of tiglic acid and related metabolites via LC-MS or GC-MS.
• Critical in pharmaceutical research for pharmacokinetic (PK) and drug metabolism studies.
• Facilitates method development and validation in analytical laboratories to meet regulatory compliance (e.g., FDA, EMA).
• Applied in metabolomics and biomarker discovery research for precise isotope dilution analysis.
• Supports agrochemical analysis for the detection and quantification of pesticide residues or degradation products.
• Enables stable isotope labeling studies to investigate chemical and biochemical reaction mechanisms.
• Employed in the synthesis of other deuterium-labeled complex molecules for research purposes.

Basic Information

Product Name	Tiglic Acid-D3
CAS No.	19146-57-7
Molecular Formula	C5H5D3O2
Molecular Weight	103.13 g/mol
Synonyms	(E)-2-Methyl-2-butenoic-3,4,4-d3 acid; (E)-2-Methylcrotonic-3,4,4-d3 acid; Tiglinic-3,4,4-d3 acid; 2-Methyl-trans-2-butenoic-3,4,4-d3 acid; trans-2-Methyl-2-butenoic-3,4,4-d3 acid; Angelic acid isomer-d3; 2,3-Dimethylacrylic-d3 acid
EINECS	Contact for details

Quality Control

Every batch of Tiglic Acid-D3 is produced and analyzed under strict quality management protocols to ensure exceptional isotopic and chemical purity, which is critical for its role as an analytical standard. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) providing detailed specifications for isotopic enrichment (D-atom %), chemical purity, and identity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.