Description

(R)-(+)-2-Phenyl-1-Propanol CAS NO 19141-40-3 is a high-purity chiral alcohol, specifically the (R)-enantiomer of 2-phenyl-1-propanol, which serves as a critical chiral building block and resolving agent in advanced organic synthesis. Its value lies in its ability to impart stereochemical control, enabling the production of enantiomerically pure pharmaceuticals, agrochemicals, and specialty materials. This compound is essential for research and manufacturing chemists in the pharmaceutical, fragrance, and fine chemical industries who require high optical purity intermediates for asymmetric synthesis and chiral resolution processes.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutics where stereochemistry is crucial for efficacy.
• Chiral Resolving Agent: Used to separate racemic mixtures of acids and other compounds via diastereomeric salt formation or esterification, a fundamental technique in producing single-enantiomer products.
• Asymmetric Synthesis Catalyst/Ligand Precursor: Serves as a starting material for synthesizing chiral ligands and organocatalysts used in metal-catalyzed and organocatalytic asymmetric reactions.
• Fragrance and Flavor Ingredient: Employed in the research and development of high-value aromatic compounds, contributing to complex scent and flavor profiles due to its phenyl-bearing structure.
• Agrochemical Synthesis: A building block for creating chiral pesticides and herbicides, where the specific enantiomer can have significantly different biological activity and environmental impact.
• Material Science Research: Utilized in the development of chiral polymers, liquid crystals, and other advanced materials with specific optical or mechanical properties.

Basic Information

Product Name	(R)-(+)-2-Phenyl-1-Propanol
CAS No.	19141-40-3
Molecular Formula	C9H12O
Molecular Weight	136.19 g/mol
Synonyms	(R)-(+)-2-Phenylpropan-1-ol; (R)-1-Phenyl-2-propanol; (R)-2-Phenyl-1-propanol; (R)-α-Methylbenzyl alcohol; (R)-α-Methylbenzenemethanol; (R)-Styryl methyl alcohol; (R)-1-Hydroxy-1-phenylpropane; (+)-(R)-2-Phenyl-1-propanol
EINECS	242-842-4

Quality Control

Our (R)-(+)-2-Phenyl-1-Propanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC or GC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and specific impurity profiles are provided with every shipment. We support compliance with cGMP, ISO, and other relevant regulatory frameworks for pharmaceutical and fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC/GC)	≥ 99.0% ee
Specific Rotation [α]20/D	+40° to +44° (c=1 in ethanol)
Refractive Index n20/D	1.520 - 1.525
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.