Description

(R)-1-Chloro-2-Propanol CAS NO 19141-39-0 is a high-purity chiral building block and intermediate of significant importance in asymmetric synthesis. Its value lies in its utility for introducing the (R)-configured propylene oxide moiety into target molecules, enabling the production of enantiomerically pure compounds. This chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require optically active intermediates for advanced R&D and production.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly β-blockers and other cardiovascular drugs.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and pesticides for enhanced efficacy.
• Asymmetric Catalyst Ligand Preparation: Serves as a starting material for synthesizing chiral ligands used in homogeneous catalysis.
• Fine Chemical Production: Building block for flavors, fragrances, and other high-value specialty chemicals requiring specific stereochemistry.
• Polymer Modification: Intermediate for creating chiral monomers or modifying polymer chains to impart specific optical or physical properties.
• Academic & Industrial Research: Valuable reagent in methodological development and scale-up studies for chiral synthesis.

Basic Information

Product Name	(R)-1-Chloro-2-Propanol
CAS No.	19141-39-0
Molecular Formula	C3H7ClO
Molecular Weight	94.54 g/mol
Synonyms	(R)-1-Chloro-2-propanol; (R)-1-Chloro-2-hydroxypropane; (R)-2-Hydroxypropyl chloride; (R)-Chloropropanol; (R)-α-Chloroisopropyl alcohol; (R)-Propylene chlorohydrin; (R)-1-Chloro-propan-2-ol; (R)-1-Chloro-2-propyl alcohol
EINECS	242-826-7

Quality Control

Our (R)-1-Chloro-2-Propanol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, enantiomeric excess (e.e.), and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. The product is hygroscopic (moisture-sensitive); ensure containers are sealed after use to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Enantiomeric Excess (Chiral GC/HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details
Refractive Index	Contact for details
Density	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.