Description

Pentanedioic-2,2,4,4-D4 Acid is a deuterium-labeled analog of glutaric acid, a dicarboxylic acid of significant importance in research and analytical chemistry. This stable isotope-labeled compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring precise and accurate measurements. It is primarily needed by researchers and analytical laboratories in the pharmaceutical, metabolomics, and environmental science sectors for advanced spectroscopic studies and method development.

Application

• Internal Standard for Mass Spectrometry (MS): Used in quantitative LC-MS and GC-MS analysis for accurate measurement of glutaric acid and related metabolites in complex biological matrices.
• Metabolomics Research: Serves as a critical tracer in metabolic pathway studies, flux analysis, and biomarker discovery.
• Pharmaceutical Development: Employed in drug metabolism and pharmacokinetics (DMPK) studies to track the fate of drug molecules and their metabolites.
• Analytical Reference Standard: Provides a high-purity, isotopically labeled reference material for method validation and calibration.
• Biochemical Research: Used in enzymatic assays and studies of metabolic disorders related to dicarboxylic acid metabolism.
• Environmental Analysis: Can be applied in tracing environmental pollutants and studying biodegradation processes.

Basic Information

Product Name	Pentanedioic-2,2,4,4-D4 Acid
CAS No.	19136-99-3
Molecular Formula	C5H2D4O4
Molecular Weight	136.13 g/mol
Synonyms	Glutaric-2,2,4,4-d4 Acid; [2H4]-Glutaric Acid; 1,5-Pentanedioic-2,2,4,4-d4 Acid; Deuterated Glutaric Acid; Glutaric Acid-d4; Pentanedioic-d4 Acid; 1,3-Propanedicarboxylic-2,2,4,4-d4 Acid
EINECS	Contact for details

Quality Control

Our Pentanedioic-2,2,4,4-D4 Acid is manufactured under strict quality systems to ensure high isotopic purity and chemical integrity. Each batch is characterized by advanced spectroscopic techniques, including NMR and mass spectrometry, to confirm deuteration level and chemical purity. Certificates of Analysis (COA) detailing isotopic enrichment (typically >98 atom % D), chemical purity (by HPLC), and other critical parameters are provided to guarantee reliable performance as an analytical standard.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 98 atom % D
Chemical Purity (Titration)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.